The goals of this program are to improve recognition of acute coronary syndrome (ACS). After hearing and assimilating this program, the clinician will be better able to:
Background: missed acute coronary syndrome (ACS) in emergency medicine accounts for 20% of paid malpractice claims; medical malpractice cases — 60% to 70% focus on inadequate history; 25% to 50% focus on misdiagnosis with electrocardiography (ECG)
Failure to obtain and document adequate history: common reason for malpractice claim; history often overlooked in favor of highly sensitive troponins, sestamibi scans, and coronary computed tomography angiography; documentation — perform and record good history of present illness; use “OPQRST” mnemonic (ie, onset of symptoms, precipitating factors, quality and radiation of pain, severity, and timing); detailed thorough history of present illness results in broader differential diagnosis; speaker uses “OLD CARTS” mnemonic (onset, location/radiation, duration, character, aggravating factors, relieving factors, timing, and severity); document all information acquired while taking history; history rigorously dissected by attorneys during medical malpractice cases; defense response — adequate history taken but not recorded; history comprises only one component of any accelerated diagnostic protocol (ADP) (ie, history accounts for 20% of HEART [history, ECG, age, risk factors, troponin] score); performing and documenting complete history provides best defense against medical malpractice claims
Misdiagnosis: similar symptoms — reflux esophagitis or peptic ulcer disease most common misdiagnoses in missed cases of ACS; in cardiology literature, ≤50% of patients experiencing acute myocardial infarction (MI) or unstable angina report increase in belching during incident; check ECG to avoid overlooking ACS; symptoms classic for another diagnosis — 20% of patients with ACS described feeling burning or indigestion; avoid being misled by specific words patients use; response to therapy — studies indicate 15% of patients experience some relief from antacids (8% report complete relief); avoid using response to antacids as diagnostic tool; associated factors — in study of >10,000 patients with MI, 8% reported that, when pain began, they had been eating a meal; gastroesophageal reflux disease (GERD) and ACS often co-exist (ie, GERD more common in cardiac patients than in noncardiac patients); consider carefully before discharging patient with diagnosis of GERD; GERD most common misdiagnosis in patients with inferior wall ST elevation myocardial infarction (STEMI)
Failure to appreciate ACS in young patients: old rule about ACS occurring in women 55 to 65 yr of age or older and in men 45 to 55 yr of age or older no longer applies; ACS reported in preadolescent children; atherosclerosis — incidence increasing; pathologists identified significant atherosclerosis in soldiers killed in Korean and Vietnam Wars; Joseph et al (1993) reported on autopsy findings from 111 patients with average age 26 yr; significant atherosclerotic disease identified in 75% of individuals (20% with multivessel disease); hyperlipidemia — current generation of children expected to have shorter lives than their parents because of unhealthy diet and obesity; American Academy of Pediatrics actively debated routinely treating children with statin drugs; in 2009, 2.8 million prescriptions written for statins to treat hyperlipidemia in children; cardiologists predict increasing incidence of teenagers with STEMI over next decade
Failure to recognize ACS in atypical presentations
Women: two-thirds of cases in medical malpractice literature involve women in their 30s, 40s, and early 50s; young and premenopausal women do experience MI; painless presentations more common in women; ACS can present with isolated arm pain, radiation of pain to right side, or isolated pain in neck, jaw, or upper back; McSweeney et al (2003) — studied prodromal symptoms among women diagnosed with MI; only 30% reported chest pain; dyspnea, sleep disturbance, and fatigue (71%) reported most frequently; patient reports of feeling “wiped out” or tired for no apparent reason common among medical malpractice cases; check ECG in these patients
ACS as upper abdominal pain: problems in chest can produce upper abdominal pain; problems in abdomen can produce chest pain; check ECG in patients with upper abdominal pain without localized tenderness; 12% of elderly patients with ACS present with upper abdominal pain rather than chest pain
Overreliance on troponin levels: avoid overlooking history and ECG in favor of troponin levels; ≈50% of medical malpractice cases document normal troponin level and ignore history or diagnostic ECG; biomarker-negative ACS does exist; abnormal ECGs often ignored because troponin level documented as normal; no validated ADPs support solely relying on troponin to rule out ACS
Conclusion: use externally validated ADPs (eg, HEART, ADAPT); use ADPs properly (avoid “going rogue”); medical malpractice attorneys use ADPs (especially HEART score); calculate actual score and document in chart; perform and document thorough history; avoid exclusion of ACS solely based on reflux symptoms (most common misdiagnosis); no age too young to consider ACS; increase suspicion for ACS in young women; check ECG in patients with upper abdominal pain and no significant tenderness
Dezman ZD et al: Utility of the history and physical examination in the detection of acute coronary syndromes in emergency department patients. West J Emerg Med, 2017 Jun;18(4):752-60; Fanaroff AC et al: Does this patient with chest pain have acute coronary syndrome?: The rational clinical examination systematic review. JAMA, 2015 Nov 10;314(18):1955-65; Graham G: Acute coronary syndromes in women: recent treatment trends and outcomes. Clin Med Insights Cardiol, 2016 Feb;10:1-10; Joseph A et al: Manifestations of coronary atherosclerosis in young trauma victims--an autopsy study. J Am Coll Cardiol, 1993 Aug;22(2):459-67; Long B et al: An end-user’s guide to the HEART score and pathway. Am J Emerg Med, 2017 Sep;35(9):1350-5; Mahler SA et al: Safely identifying emergency department patients with acute chest pain for early discharge. Circulation, 2018 Nov;138(22):2456-68; McSweeney JC et al: Women’s early warning symptoms of acute myocardial infarction. Circulation, 2003 Nov;108(21):2619-2; Quinn GR et al: Missed diagnosis of cardiovascular disease in outpatient general medicine: Insights from malpractice claims data. Jt Comm J Qual Patient Saf, 2017 Oct;43(10):508-16; Smaardijk VR et al: Sex- and Gender-Stratified Risks of Psychological Factors for Incident Ischemic Heart Disease: Systematic Review and Meta-Analysis. J Am Heart Assoc, 2019 May;8(9):e010859.
For this program, members of the faculty and planning committee reported nothing to disclose.
Dr. Mattu was recorded at Rocky Mountain Winter Conference on Emergency Medicine, held February 23-27, 2019, in Steamboat Springs, CO, and presented by SCP Health. For information about upcoming CME activities sponsored by SCP Health, please visit SCP-Health.com. The Audio Digest Foundation thanks Dr. Mattu and SCP Health for their cooperation in the production of this program.
The Audio- Digest Foundation is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The Audio- Digest Foundation designates this enduring material for a maximum of 0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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EM370301
This CME course qualifies for AMA PRA Category 1 Credits™ for 3 years from the date of publication.
To earn CME/CE credit for this course, you must complete all the following components in the order recommended: (1) Review introductory course content, including Educational Objectives and Faculty/Planner Disclosures; (2) Listen to the audio program and review accompanying learning materials; (3) Complete posttest (only after completing Step 2) and earn a passing score of at least 80%. Taking the course Pretest and completing the Evaluation Survey are strongly recommended (but not mandatory) components of completing this CME/CE course.
Approximately 2x the length of the recorded lecture to account for time spent studying accompanying learning materials and completing tests.
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